MemProtMD: Automated insertion of membrane protein structures into explicit lipid membranes

MemProtMD: Automated insertion of membrane protein structures into explicit lipid membranes

Stansfeld et al. 2015 (Sansom Lab) - Structure (Cell)

• Membrane proteins structures often resolved in the absence of their native lipid environment
• Automated method to identify membrane proteins in the PDB and insert into an explicit lipid bilayer
• First performed at the CG level, then backtrace to the all-atom level
• Can analyze recently determined protein structures for locations in the membrane, lipid-protein interactions and functional implications